Biosafety manual 2004

This biosafety manual has been developed by the environmental health and safety ehs department at michigan state university. For more than 20 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in. No work with biosafety level 4 agents may be conducted at yale university. Good microbiological technique and appropriate use of biosafety equipment by well trained staff remain the.

However, this documents will be effective until the new changes are incorporated in the manual. Agents which are not associated with disease in healthy adult humans. All these manuals are available at the medical sciences campus web page. This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. Graphics kindly provided by cuh2a, princeton, nj, usa who biosafety manual 3rd ed. Published in 2004, years have passed in this fast evolving field.

Biosafety manual the revision of these documents is also performed to comply with the changes in regulations of the local and states agencies. Laboratory biosafety manual world health organization for more than 20 years, since it was first published in 1983, the laboratory. Laboratory biosafety manual third edition for more than 20 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in laboratories at all levels. Laboratory biosafety manual who world health organization. A microorganism unlikely to cause human or animal disease. Jun 17, 2019 who laboratory biosafety manual lbm first published in 1983 and included. Microorganism risk groups risk group classification nih guidelines for research involving recombinant dna molecules 2009 world health organization laboratory biosafety manual 3rd edition 2004 risk group 1 agents that are not associated with. Chapter 1620 canadian biosafety handbook, second edition. A thorough, evidencebased and transparent assessment of the risks allows safety measures to be balanced with the actual risk of working with.

Pdf laboratory biosafety manual fourth edition ahmed f. The third edition of the who laboratory biosafety manual is a helpful reference and guide to nations that accept the challenge to develop and establish national codes of practice for securing microbiological assets, yet ensuring their availability for clinical. Risk group 2 agents that are associated with human disease which is rarely serious and for which preventive or. Laboratory biosafety manual world health organization.

The manual focuses on biosafety levels 1 and 2, as over 99% of yale laboratories fall within these designations. Address the most commonly asked questions from faculty, staff and students on general biosafety, pathogens, and recombinant. Biosafety laboratory biosafety describes the containment principles, technologies and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release. World health organization who laboratory biosafety manual 2004. The sri lanka college of microbiologists felt the need to revise the manual with regards to the current development in laboratory safety. Principles and methods of biosafety in judging the effectiveness of measures intended to ensure biosafety, it may be helpful to know which goals, principles, and methods of biosafety measures have been employed and to evaluate the scienti. Biosafety in microbiological and biomedical laboratories cdc. No or low individual and community risk a microorganism that is unlikely to cause human or animal disease. Who continues to provide international leadership in biosafety through this third edition of the manual by addressing biological safety and security issues facing. Who laboratory biosafety manual lbm revision update. Risk groups are the result of a classification of microbiological agents based on their association with, and resulting severity of, disease in humans. This manual does not include working in biosafety level 3 or 4 laboratories. World health organization geneva 2004 laboratory biosafety manual third edition 2. A separate manual is available for researchers working in biosafety level 3 research laboratories.

The manual is part of msus biosafety program, which was established to accomplish the following goals. Biosafety manual 3rd edition 2004 risk group 1 agents that are not associated with disease in healthy adult humans. Who published the first edition of the laboratory biosafety manual in 1983. Laboratory biosafety manual were published in 1993 and 2004 respectively 2,3. Seroprevalence of hepatitis b virus infection hbsag in rural blood donors, moba, tanganyika province, democratic republic of congo 2014 to 2016. Containment standards for facilities handling aquatic. This publication was supported by grantcooperative agreement number u50ccu01244508 from the centers for disease control and prevention cdc, atlanta, ga, usa.

The uw biosafety manual provides students, staff, and faculty at uw with information that is necessary to protect them and the surrounding community from possible hazards associated with the use of biohazardous agents and recombinant or synthetic dnarna recdna molecules. Risk group 2 agents that are associated with human disease which is rarely serious and for. This manual was developed based on the containment standards and operational guidelines described in that document. Yale school of public health biosafety, biosecurity and the. This biosafety manual is applicable to all laboratory, research, teaching, service, and support activities that may involveexposure to biohazard agents or materials ous or otherwisecomes under the purview of the institutional biosafety committee ibc at the university of montana. Good microbiological technique and appropriate use of biosafety equipment by well trained staff. Risk group 2 agents that are associated with human. Training of personnel on the emergency procedures is essential to make certain that personnel, particularly new personnel, are aware of and familiar with the procedures to follow prior to an. Who laboratory biosafety manual 2004 who should attend all university employees, students, and volunteers who engage in research human body fluids including blood, urine, saliva, etc. With each new version, who continues to provide international leadership on biosafety by addressing emerging issues, technologies and challenges, and providing guidance on best practices.

The laboratory biosafety guidelines, 3rdedition, 2004, published by health canada, was the key document governing the use of biohazardous materials in canada until 20. Basic, containment and maximum containment bsl yet to be defined the current 3rd edition was published in 2004 years have passed in this fastevolving field with advancing technologies. Who risk group definitions are in whos laboratory biosafety manual who 2004. The manual now covers risk assessment and the safe use of recombinant dna technology, and provides. Biosafety manual for medical laboratories sri lanka college.

Biosafety guidelines who laboratory biosafety manual, 3rd edition, 2004 nih rdna guidelines, april 2002 cdcnih primary containment for biohazards. Once developed, the erp or a summary of the plan can be included in a facilitys biosafety manual and communicated to all facility personnel appropriately. What might be a recommendation for one facility becomes a requirement for another depending on the interpretation of the facility usage and the projected needs. Old dominion university has developed this biosafety manual to provide guidance to all faculty, staff, and students theon safe handling of biological materials and the proper safety practices to minimize the risk of exposure to potentially infectious materials. The third edition stresses throughout the importance of personal responsibility. Additional guidance is provided in biosafety in microbiological and biomedical laboratories, published by the centers for disease control national institutes of health. Laboratory biosafety manual were published in 1993 and 2004 respectively. The third edition of the who laboratory biosafety manual is a helpful reference and guide to nations that accept the challenge to develop and establish national codes of practice for securing microbiological assets, yet ensuring their availability for clinical, third edition who laboratory biosafety manual, 3rd edition. World health organization who 2004 laboratory biosafety manual. The national institutes of health us, office of biotechnology activities. Biocontainment conditions office of research support and. Work involving biosafety level 4 risk group 4 organisms is prohibited at pace university. Laboratory biosafety manual states that no biosafety cabinet or other facility or procedure alone guarantees safety unless the users operate safe techniques based on informed understanding.

Containment standards for facilities handling aquatic animal pathogens. Protect personnel from exposure to infectious agents prevent environmental contamination. Pis are required to submit an application to use rdna, biohazardous agents, or unfixed human fluids and tissues prior to the initiation of the research. The biosafety manual consists of this orientation plus a collection of sops specific to biosafety as well as some sops from the animal care collection with biosafety specific material. For more than 20 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in laboratories at all levels. Centers for disease control cdc, and purdue university policies and the biosafety manual. Classification of infective microorganisms by risk group who laboratory biosafety manual, 3rd ed, 2004 risk group 1 no or low individual and community risk. World health organization who 2004 laboratory biosafety. Who library cataloguinginpublication data world health organization. The manual encouraged countries to accept and implement basic concepts in. Who extended biosafety advisory group bag meetings, geneva, 2425 november 2014, and 15 december 2016 key recommendation 2014 revision to the who biosafety manual is both a necessary and a priority key recommendation 2016 general agreement for the proposed modifications to the manual, the revision of which remains a priority. This biosafety manual represents the institutional practices and procedures for the safe use and handling of biological materials, recombinant dna and synthetic nucleic acids at stanford university.

With each new version, who continues to provide international leadership on. Selection, installation and use of biological safety cabinets, 2000 cdcnih biosafety in microbiological and biomedical laboratories, 4th edition, 1999. Laboratory biosafety manual third edition ewhs bmet library. Biosafety manual biosafety manual for the university of nevada, reno biosafety manual introduction chapter 1. Laboratory biosafety manual 3rd edition 2004 risk group 1 agents that are not associated with disease in healthy adult humans. The first publication of the biosafety manual had been done by the consultant microbiologists and staff at medical research institute in 2004 with collaboration of ministry of health. Publications of the world health organization can be obtained from marketing and. More generally, the bmbl describes four standard biological safety levels bsl, each of which includes a combination of practices, safety equipment, and laboratory features that are summarized in. Feb 24, 2021 this biosafety manual represents the institutional practices and procedures for the safe use and handling of biological materials, recombinant dna and synthetic nucleic acids at stanford university. For this new edition, the manual has been extensively revised and expanded. World health organization laboratory biosafety manual 3rd edition 2004. Biosafety, biosecurity and dualuse research of concern. The bsls described in this manual should be differentiated from risk groups, as described in the nih guidelines and the world health organization laboratory biosafety manual. World health organization geneva 2004 laboratory biosafety manual third edition.